Methamphetamine dependence · Mexico City
Ibogaine Treatment For Methamphetamine Addiction
The thinnest evidence we cite, the strictest heart screen we run, and a page that says both before you call.
Ibogaine is being asked to do something different for methamphetamine than it does for opioids. There is no opioid-type withdrawal to interrupt. What there is: a crash, a craving that outlasts it, a heart that meth has been working for years, and a supply that is no longer only meth. This page covers all 4, and what each one changes about whether we treat you.
The short answer
What is ibogaine treatment for methamphetamine addiction?
In 1 sentence
Ibogaine treatment for methamphetamine addiction is 1 physician-supervised dose, given for craving rather than withdrawal, under the strictest cardiac screening we run.
Mexico City · 7 days · $12,500
It runs as the same 7-day inpatient program as every other dependence we treat: a licensed Mexico City facility, a cardiologist, an emergency physician and an ACLS-trained nurse in the room, continuous 12-lead ECG through the session and the night, then 90 days of clinical follow-up.
What is different is the claim. For opioids, ibogaine interrupts a physical withdrawal that the published studies measured. For methamphetamine there is no equivalent withdrawal, and there is no published human study of ibogaine in a methamphetamine-dependent group. What we can point to is a cocaine series, and inference from it. We say that here and we say it again on the screening call.
It is not a cure, it is not FDA approved, and it is not given to anyone whose heart, electrolytes, medication list or mental state fall outside written thresholds.
Program
7 nights inpatient, 1 supervised dose on day 3, then 90 days of structured follow-up.
Price
$12,500, itemised, with 5 stated exclusions. Screening costs nothing and happens before any deposit.
Screening tier
The strictest on the site: a cardiac history going back years, a lower QTc threshold than opioids, an echocardiogram when the cardiologist asks.
Evidence grade
Inferred from cocaine data. 0 published human studies of ibogaine for methamphetamine. We do not quote a success rate.
What ibogaine is asked to do
Meth has no withdrawal to interrupt. That changes the claim.
Opioid withdrawal is a physical syndrome with a scale to measure it, and the ibogaine studies measured it falling. Stopping methamphetamine produces a crash instead: sleep, appetite, a flat or low mood, and a craving that outlasts all 3. None of that needs a drug to survive. So the question for meth is narrower, and the honest answer to each part of it is different.
Claim 1
Interrupt a physical withdrawal
There is nothing to interrupt. The crash is miserable. It is not the medical emergency alcohol withdrawal can be, and the mood that comes with it is watched by a physician rather than waited out. Anyone selling you an ibogaine “detox” for meth is describing a problem you do not have.
Claim 2
Reduce craving
In 89 cocaine-dependent inpatients, craving scores fell on every scale measured at discharge and at 1 month. Cocaine and meth both act on the same dopamine system, so we treat that as the best available signal. It is a signal from a different drug, and it stops at 1 month.
Claim 3
Change what happens at 6 months
No study has followed stimulant patients that long after ibogaine. We do not know, so we do not say. The 90 days of follow-up exist partly because this is where the evidence runs out.
The working explanation, for what it is worth: ibogaine and its long-lasting metabolite noribogaine act on the serotonin and dopamine transporters and on opioid and NMDA receptors at once, and in animals they reduce stimulant self-administration. That is a mechanism, not an outcome. The opioid page sets the mechanism out in full.
The risk we screen for
Meth works the heart for years. Ibogaine asks a lot of it in a day.
Ibogaine blocks the hERG potassium channel, prolongs the QT interval and slows conduction. Methamphetamine drives heart rate and blood pressure up on every use and, over years, can remodel the heart muscle itself. That is why the stimulant screen goes back years rather than weeks, and why we decline a higher share of stimulant cases than opioid cases.
Cardiomyopathy
Long-term use can weaken and enlarge the left ventricle. In 1 Southern California series the share of new cardiomyopathy cases linked to methamphetamine rose from 1.8% in 2009 to 5.6% in 2014, and it is often found in people who never had a symptom they recognised as cardiac.
The echo decides
Damage on the echocardiogram is a no, whatever the EKG says.
Rhythm and the QT interval
A fast heart with a prolonged QT is a common finding in people presenting after methamphetamine use, and ventricular arrhythmias are documented. A heart that already runs long cannot be given a drug that lengthens it further, which is why the stimulant threshold sits below the opioid one.
Stricter threshold
Your EKG is read against a lower QTc line than an opioid patient’s.
Pulmonary hypertension
Methamphetamine is a recognised cause of pulmonary arterial hypertension, and the meth-associated form tends to present more severely and progress faster than other kinds. It rarely shows on an EKG alone, which is 1 reason the cardiologist can ask for an echocardiogram before any date is offered.
Echo when asked
The cardiologist orders it. It is not optional and it is not a formality.
A history that predates the test
Chest pain, palpitations, fainting, any emergency visit linked to use, any prior cardiac event. A clean EKG today does not cancel an event 3 years ago. We ask for the whole history, and we mean years, because the trace only shows the heart you have this morning.
Event in history
A stimulant-linked cardiac event, chest pain or arrhythmia is a permanent no.
One thing the cardiology literature also says: some methamphetamine-associated cardiomyopathy recovers with sustained abstinence, and scarring in the muscle is what predicts when it will not. So a damaged echocardiogram today is a no today. If a repeat echocardiogram after months without use reads normal, the case can be looked at again from the beginning, EKG and labs included. That is not a promise and it is not quick. It is the difference between a door that is closed and a door that is locked.
Timing
The drug leaves quickly. The crash does not, and the heart is slower still.
For fentanyl the question is a washout, because the drug itself lingers. Methamphetamine is the opposite problem: it is gone from the blood within days, and what lingers is the state it leaves behind. Dosing is planned around that state, not around a test result.
Hours
The drug clears
Heart rate and blood pressure come down over the first day or 2. The EKG we would see now is still the EKG of recent use.
Days 1 to 3
The crash
Long sleep, a large appetite, a low or flat mood. Not a medical emergency, and nobody is dosed in the middle of it.
Days 3 to 10
The acute phase
Sleep settles unevenly, craving is at its strongest and mood at its lowest. This is where craving peaks, which is why these days are spent here rather than at home.
Weeks 2 to 4
Subacute
Energy and sleep improve. Craving and mood lag behind them. This is also where the follow-up calls do most of their work, because you are home by then.
What has to be true on dosing day
We do not publish how many days after last use the dose happens, because for methamphetamine the right answer is a state rather than a date, and a number on a website gets held against a body it was not written for. The physician sets it for your case, in writing, before any deposit.
- The crash has passedA state the physician confirms in person, not a number of days we publish
- Repeat EKG matches the pre-travel traceRead against the stricter stimulant threshold, on day 1 and again before dosing
- Potassium and magnesium in rangeThe crash empties both, and low levels of both make ibogaine’s QT effect worse
- No active psychotic symptomsConfirmed by the psychiatrist, in person, not on a form
- You have slept and eatenThe session runs for hours and the night after it is monitored. You go into it rested
The question no opioid page has
Psychosis is asked about by name, and it can be the reason for a not yet.
Methamphetamine produces psychotic symptoms in a large share of dependent users, usually paranoia and hallucinations that fade with abstinence and return with use. Ibogaine is itself an hours-long psychoactive experience. Those 2 facts cannot be allowed to overlap, so this is screened for directly rather than hoped about.
60%
of 278 methamphetamine-dependent people reported psychotic symptoms in at least 1 month of a longitudinal study, with no prior schizophrenia or mania in any of them.
11x
the odds of psychotic symptoms in months with 16 or more days of use, compared with months of no use. At 1 to 15 days the odds were 4 times higher.
Active symptoms
A not yet. The date moves until the symptoms have resolved, and the psychiatrist decides that, not a calendar and not you.
Resolved history
A psychosis that cleared when you stopped using is reviewed case by case by the psychiatrist during screening, and again in person on day 1. It is not a no on its own.
Primary illness
A psychotic illness diagnosed independently of methamphetamine is reviewed by the psychiatrist and the bar is high. Ibogaine has not been studied in that group, and we will not be the study.
Sleep is part of this. Days without sleep on methamphetamine is a common route into psychosis, and it is also why “you have slept” is on the dosing-day list above rather than left to chance.
What is sold as meth
You may be dependent on more than 1 drug, and the second one changes the protocol.
The US methamphetamine supply is made almost entirely by Mexican cartels using the P2P method, and it is stronger and cheaper than it has ever been. It is also increasingly not only meth. 3 figures from the DEA’s 2025 National Drug Threat Assessment, and what each one changes about screening.
~97%
Average purity of seized methamphetamine in 2025, the highest ever recorded. More than 98% of samples were made by the P2P method, which is why the supply is uniform, cheap and strong.
What it changes: at this potency a stated daily amount tells us less than frequency, route and how many years you have used. We ask about pattern, not grams, and the pattern is what sets the cardiac questions.
1 in 8
Methamphetamine submissions tested by the DEA that also contained fentanyl.
What it changes: if fentanyl shows on your screen you may be opioid-dependent without knowing it. Ibogaine then has to wait for the opioid washout, and the case moves to the fentanyl protocol. Nobody is dosed on a stimulant plan while an opioid is still leaving the body.
3.2M
Methamphetamine pills seized in 2024, up from 2.6M in 2023. Pills pressed to look like Adderall are sold to people who believe they are buying a prescription stimulant.
What it changes: some people hear the word methamphetamine for the first time on our screening call. They are screened as meth patients, without judgement, because the supply lied to them and not the other way round.
None of this is asked to catch you out. A clinic that screens a 2025 methamphetamine patient as a single-drug case has stopped paying attention to the supply.
The evidence
What exists at each level, and where methamphetamine sits on it.
The honest way to read evidence is by level, not by headline. Here is every level that matters and what has been published at each one for ibogaine and stimulants. Notice which rows are empty. Then look at what the rest of medicine has for methamphetamine, because that is the fair comparison.
Level 4
None
Randomised controlled trial
No RCT of ibogaine has been published for any dependence. Texas funded $50 million of FDA-supervised ibogaine trials in 2025. They are not designed around methamphetamine and will take years to report.
Level 3
None
Human study, methamphetamine-specific
Not 1 published study has treated a methamphetamine-dependent group with ibogaine and reported outcomes. A clinic quoting you a meth success rate is quoting something that does not exist in the literature.
Level 2
2 studies, 0 meth
Human study, other stimulants
Mash and colleagues, 2018: 89 cocaine-dependent inpatients, craving fell at discharge and at 1 month, no serious adverse events, and follow-up stopped there. Schenberg and colleagues, 2014: 75 people in Brazil dependent on alcohol, cannabis, cocaine or crack, 61% abstinent at a median of 5.5 months, retrospective, self-reported, no control group. Neither included methamphetamine. When a clinic cites that 61% for meth, that is what it is doing.
Level 1
Rats
Animal studies
Ibogaine and related iboga alkaloids reduce stimulant self-administration and alter methamphetamine sensitisation in rats. That is where the mechanism story comes from. Rats are not patients, and we treat this level as a reason to study, not a reason to promise.
For comparison
What the rest of medicine has for methamphetamine
There is no FDA-approved medication for methamphetamine use disorder. The best-studied combination, bupropion with extended-release naltrexone, was tested in 403 people:
- 13.6%responded on the combination, measured by negative urine screens
- 2.5%responded on placebo, which puts the number needed to treat at 9
Contingency management, paying people to stay negative on urine screens, remains the best-supported treatment there is.
We say this because the honest frame for ibogaine is not “better than nothing”. It is “unproven, next to treatments that are proven and modest”. You should have both of those in front of you before you decide.
The papers themselves, with their limits set out, are on the what we treat page. The opioid evidence, which is where ibogaine’s case is strongest, is on the opioid page.
Who we turn away
3 columns. Only 1 of them is final.
Every answer comes in writing with the reason. Any deposit is refunded in full, and where we can we hand you a referral to a clinician near you. Nobody is passed to another clinic for a fee.
- Structural heart disease, cardiomyopathy or heart failure on the echocardiogram
- A stimulant-linked cardiac event, chest pain or arrhythmia in your history
- A QTc or conduction finding above the stricter stimulant threshold that is not caused by something correctable
- Benzodiazepine dependence as the main problemThe withdrawal can cause seizures and ibogaine does not shorten the taper
- Pregnancy or breastfeeding, and anyone under 18
- Anyone who wants the dose without the screening, the 7 days or the follow-up
- Active psychotic symptomsThe date moves until the psychiatrist confirms they have resolved
- Fentanyl on the screenThe case moves to the opioid washout first
- Potassium, magnesium or liver values out of rangePending correction and a recheck
- A day 1 EKG that does not match the trace you were approved onThe stay is refunded
- A QT-prolonging medication your own prescriber has not yet agreed a plan for
- A damaged echocardiogram that a later one, after months without use, might read differently
- How much and how often you useIt sets the plan. It does not decide the answer
- Whether you smoke, snort or injectRoute changes the cardiac questions, not the outcome
- Pills you believed were Adderall
- A psychosis that resolved when you stopped
- Using during the waitTell us and the date moves. There is no penalty for the truth
The full decline list for every dependence we treat is on what we treat.
After day 7
The dangerous weeks are 2 to 4, and they happen at home.
For opioid patients the risk after treatment is a lowered tolerance. For methamphetamine patients it is the subacute phase: the weeks when energy comes back before mood does, and a craving that was quiet in the facility returns in the place it was learned.
90
Days of follow-up
The follow-up is built around that window. It is the same 90-day structure as every other case we treat, and for methamphetamine the calls in weeks 2 to 4 are the ones that matter most, because that is when craving and mood are still lagging behind energy.
Days 1 to 30
Weekly clinician calls on a scheduled day. Sleep, appetite, mood and craving are tracked, because a change in any 1 of them is usually the earliest signal.
Days 45, 60, 90
Longer calls with the psychiatrist who saw you here, not a coordinator with a script. If a second session is ever discussed, it starts in these calls and is screened from the beginning.
Handover
A written clinical summary goes to your own physician with a referral list of US clinicians. If fentanyl was in your supply, naloxone at home is part of the discharge conversation.
Common questions
Methamphetamine and ibogaine, answered plainly.
Most of what decides a methamphetamine case is an echocardiogram, an EKG and a psychiatrist’s conversation, which is why the screening call exists and why it is free.
Does ibogaine work for meth addiction?
No published study has tested it in methamphetamine-dependent people, so nobody can answer that with evidence. What exists: cocaine craving fell at discharge and at 1 month in an 89-person inpatient series, animal studies show reduced stimulant self-administration, and the mechanisms overlap. We treat methamphetamine on that inference, we say so on the first call, and we do not quote a success rate because there is none to quote.
Is there a washout for meth like there is for fentanyl?
Not in the same sense. Methamphetamine clears from the blood within days. What we wait for is a state: the crash passed, sleep and appetite returning, a repeat EKG that matches your pre-travel trace, electrolytes in range and no active psychotic symptoms. The physician confirms all of it in person before dosing. We do not publish a number of days, because for meth the number is set by your body rather than by the drug.
Why is the cardiac screening stricter for meth than for opioids?
Because methamphetamine damages the heart in ways that persist after use stops: cardiomyopathy, arrhythmia and pulmonary hypertension are all documented. Ibogaine prolongs the QT interval and slows conduction. Stacking the second on a heart already changed by the first is the risk we will not take, so the cardiac history goes back years, the QTc threshold is lower, and the cardiologist can ask for an echocardiogram before a date is offered.
I have had meth psychosis before. Does that rule me out?
Not on its own. A psychosis that resolved when you stopped is reviewed by the psychiatrist during screening and again in person on day 1. Active symptoms are a not yet: the date moves until they have resolved. A psychotic illness diagnosed independently of methamphetamine is a different matter and the bar is high, because ibogaine has never been studied in that group.
What if there was fentanyl in my meth?
Assume there may have been. In the DEA’s 2025 assessment, 1 in 8 methamphetamine submissions contained fentanyl. If it shows on your screen, the case moves to the opioid protocol and the longer fentanyl washout, and days 1 and 2 are planned as an opioid case. Nobody is dosed on a stimulant plan while an opioid is still leaving the body. Naloxone at home becomes part of the discharge conversation.
Can I be screened while I am still using?
Yes, and most people are. Screening happens while you are using and nobody is asked to stop alone before travelling. What we need is an honest account: how often, by what route, for how many years, and when you last used, including anything you believed was a prescription pill. The crash is not the emergency alcohol withdrawal can be, but it is spent here, under a physician, rather than at home.
What are my options if you decline me?
You get the reason in writing and any deposit back in full. For methamphetamine there is no approved medication, but there are treatments with evidence behind them: contingency management is the best supported, and bupropion with extended-release naltrexone helped 13.6% of patients against 2.5% on placebo in the largest trial. You get a referral list of US clinicians, the same list our patients get, and nobody is passed to another clinic for a fee.
What does it cost, and what is not included?
$12,500 for the 7 days and the 90 days of follow-up. Not included: flights, the EKG, labs and any echocardiogram your own doctor orders before screening, extra nights beyond 7, medications prescribed after discharge, and family accommodation outside the facility. The pricing page itemises all of it.
Screening costs nothing
Ask now. The heart screen takes longer than the call, so start it first.
3 questions on the contact page. A physician or nurse calls you back within 1 business day and tells you which tests to order at home, including the echocardiogram if the cardiologist wants one. The answer comes in writing, whether it is yes, not yet, or no.